Signal Transduction Recombinant Proteins

Human UBE2D1 Recombinant Protein (RPES2834)

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SKU:
RPES2834
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Signal Transduction

Description

system_update_altDatasheet

Human UBE2D1 Recombinant Protein

Ubiquitin-conjugating enzyme E2 D1?UBE2D1?belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes; or E1s; ubiquitin-conjugating enzymes; or E2s; and ubiquitin-protein ligases; or E3s. This enzyme is closely related to a stimulator of iron transport (SFT); and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

Product Name:Human UBE2D1 Recombinant Protein (RPES2834)
Product Code:RPES2834
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Ubiquitin-conjugating enzyme E2 D1,Stimulator of Fe transport,SFT,UBC4/5 homolog,UbcH5,Ubiquitin carrier protein D1,Ubiquitin-conjugating enzyme E2(17)KB 1,Ubiquitin-conjugating enzyme E2-17 kDa 1,Ubiquitin-protein ligase D1,SFT, UBC5A, UBCH5, UBCH5A
Accession:P51668
Sequence:Met 1-Met 147
Fusion tag:N-GST
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Ubiquitin-conjugating enzyme E2 D1 is produced by our E.coli expression system and the target gene encoding Met1-Met147 is expressed with a GST tag at the N-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:42.9 kDa
AP Mol Mass:25&50 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 50mM HEPES;150mM NaCl;2mM DTT;10% Glycerin;pH7.5.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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system_update_altDatasheetHuman UBE2D1 Recombinant Protein Ubiquitin-conjugating enzyme E2 D1 (UBE2D1); a member of human E2 ubiquitin-conjugating enzymes; is closely related to SFT; which is sho