Signal Transduction Recombinant Proteins
Human UBE2D1 Recombinant Protein (RPES1575)
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- SKU:
- RPES1575
Description
system_update_altDatasheet
Human UBE2D1 Recombinant Protein
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1); a member of human E2 ubiquitin-conjugating enzymes; is closely related to SFT; which is short for stimulator of iron (Fe) transport. In other words; UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis; as previously published for SFT. Moreover; a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.
| Product Name: | Human UBE2D1 Recombinant Protein (RPES1575) |
| Product Code: | RPES1575 |
| Size: | 50µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Ubiquitin-conjugating enzyme E2 D1,Stimulator of Fe transport,SFT,UBC4/5 homolog,UbcH5,Ubiquitin carrier protein D1,Ubiquitin-conjugating enzyme E2(17)KB 1,Ubiquitin-conjugating enzyme E2-17 kDa 1,Ubiquitin-protein ligase D1,SFT, UBC5A, UBCH5, UBCH5A |
| Accession: | P51668 |
| Sequence: | Ala 2-Met 147 |
| Fusion tag: | N-His |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the human UBE2D1 (P51668) (Ala 2-Met 147) was expressed; with a polyhistide tag at the N-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 18.3 kDa |
| Formulation: | Lyophilized from sterile 25mM Tris; 100mM NaCl; 20% glycerol; 0.05% Tween |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Signal Transduction |
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