Signal Transduction Recombinant Proteins

Human UBE2D1 Recombinant Protein (RPES1575)

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SKU:
RPES1575
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Signal Transduction

Description

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Human UBE2D1 Recombinant Protein

Ubiquitin-conjugating enzyme E2 D1 (UBE2D1); a member of human E2 ubiquitin-conjugating enzymes; is closely related to SFT; which is short for stimulator of iron (Fe) transport. In other words; UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis; as previously published for SFT. Moreover; a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.

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