Signal Transduction Recombinant Proteins

Human UBE2D1 Recombinant Protein (RPES1575)

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SKU:
RPES1575
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Signal Transduction

Description

system_update_altDatasheet

Human UBE2D1 Recombinant Protein

Ubiquitin-conjugating enzyme E2 D1 (UBE2D1); a member of human E2 ubiquitin-conjugating enzymes; is closely related to SFT; which is short for stimulator of iron (Fe) transport. In other words; UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis; as previously published for SFT. Moreover; a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.

Product Name:Human UBE2D1 Recombinant Protein (RPES1575)
Product Code:RPES1575
Size:50µg
Species:Human
Expressed Host:E.coli
Synonyms:Ubiquitin-conjugating enzyme E2 D1,Stimulator of Fe transport,SFT,UBC4/5 homolog,UbcH5,Ubiquitin carrier protein D1,Ubiquitin-conjugating enzyme E2(17)KB 1,Ubiquitin-conjugating enzyme E2-17 kDa 1,Ubiquitin-protein ligase D1,SFT, UBC5A, UBCH5, UBCH5A
Accession:P51668
Sequence:Ala 2-Met 147
Fusion tag:N-His
Endotoxin:Please contact us for more information.
Protein Construction:A DNA sequence encoding the human UBE2D1 (P51668) (Ala 2-Met 147) was expressed; with a polyhistide tag at the N-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:18.3 kDa
Formulation:Lyophilized from sterile 25mM Tris; 100mM NaCl; 20% glycerol; 0.05% Tween
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Signal Transduction Recombinant Proteins

system_update_altDatasheetHuman UBE2D1 Recombinant Protein Ubiquitin-conjugating enzyme E2 D1?UBE2D1?belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three cla