Cell Biology Recombinant Proteins

Human TXNRD1/TRXR1 Recombinant Protein (RPES1217)

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SKU:
RPES1217
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Biology

Description

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Human TXNRD1/TRXR1 Recombinant Protein

Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor the development of Drug-induced liver injury (DILI), which is the most common adverse drug reaction.

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