Human TXNL4B Recombinant Protein (RPPB5055)
- SKU:
- RPPB5055
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NX01
Description
| Product Name: | Human TXNL4B Recombinant Protein |
| Product Code: | RPPB5055 |
| Size: | 10µg |
| Species: | Human |
| Target: | TXNL4B |
| Synonyms: | Thioredoxin-like protein 4B, Dim1-like protein, TXNL4B, DIM2, DLP. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | TXNL4B protein solution (0. 5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 100mM NaCl. |
| Stability: | TXNL4B Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSFL LPKLTSKKEV DQAIKSTAEK VLVLRFGRDE DPVCLQLDDI LSKTSSDLSK MAAIYLVDVD QTAVYTQYFD ISYIPSTVFF FNGQHMKVDY GSPDHTKFVG SFKTKQDFID LIEVIYRGAM RGKLIVQSPI DPKNIPKYDL LYQDI |
TXNL4B is a member of the DIM1 family which has a vital role in pro-mRNA splicing. TXNL4B is required in cell cycle progression for S/G2 transition and interacts with PRPF6 subunit of the spliceosome.
TXNL4B produced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids (1-149 a.a) and having a molecular mass of 21.1kDa.TXNL4B is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | TXNL4B: Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition. Belongs to the DIM1 family. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 16q22.2 Cellular Component: spliceosome; U4/U6 x U5 tri-snRNP complex; snRNP U5 Biological Process: mitosis; spliceosome assembly |
| UniProt Code: | Q9NX01 |
| NCBI GenInfo Identifier: | 51702156 |
| NCBI Gene ID: | 54957 |
| NCBI Accession: | Q9NX01.1 |
| UniProt Secondary Accession: | Q9NX01,D3DWS6, |
| UniProt Related Accession: | Q9NX01 |
| Molecular Weight: | 149 |
| NCBI Full Name: | Thioredoxin-like protein 4B |
| NCBI Synonym Full Names: | thioredoxin-like 4B |
| NCBI Official Symbol: | TXNL4B�� |
| NCBI Official Synonym Symbols: | DLP; Dim2�� |
| NCBI Protein Information: | thioredoxin-like protein 4B; Dim1-like protein |
| UniProt Protein Name: | Thioredoxin-like protein 4B |
| UniProt Synonym Protein Names: | Dim1-like protein |
| Protein Family: | Thioredoxin-like protein |
| UniProt Gene Name: | TXNL4B�� |
| UniProt Entry Name: | TXN4B_HUMAN |
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