Human TXNDC17 Recombinant Protein (RPPB5052)

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SKU:
RPPB5052
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9BRA2

Description

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Product Name:Human TXNDC17 Recombinant Protein
Product Code:RPPB5052
Size:20µg
Species:Human
Target:TXNDC17
Synonyms:Thioredoxin domain containing 17, Thioredoxin-like protein 5, Protein 42-9-9, thioredoxin (Trx)-related protein 14 kDa, TRP14, TXNL5, MGC14353.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The TXNDC17 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 50mM Nacl and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMARYEE VSVSGFEEFH RAVEQHNGKT IFAYFTGSKD AGGKSWCPDC VQAEPVVREG LKHISEGCVF IYCQVGEKPY WKDPNNDFRK NLKVTAVPTL LKYGTPQKLV ESECLQANLV EMLFSED

TXNDC17 is a disulfide reductase that takes part in several redox reactions using the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. TXNDC17 has peroxidase activity and assists to eliminate cellular hydrogen peroxide.

TXNDC17 Human Recombinant produced in E. coli is a single polypeptide chain containing 147 amino acids (1-123) and having a molecular mass of 16.5kDa.TXNDC17 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9BRA2
NCBI GenInfo Identifier:14249348
NCBI Gene ID:84817
NCBI Accession:NP_116120.1
UniProt Secondary Accession:Q9BRA2,A8K7E8
UniProt Related Accession:Q9BRA2
Molecular Weight:13,941 Da
NCBI Full Name:thioredoxin domain-containing protein 17
NCBI Synonym Full Names:thioredoxin domain containing 17
NCBI Official Symbol:TXNDC17��
NCBI Official Synonym Symbols:TRP14; TXNL5��
NCBI Protein Information:thioredoxin domain-containing protein 17
UniProt Protein Name:Thioredoxin domain-containing protein 17
UniProt Synonym Protein Names:14 kDa thioredoxin-related protein; TRP14; Protein 42-9-9; Thioredoxin-like protein 5
Protein Family:
UniProt Gene Name:TXNDC17��
UniProt Entry Name:
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