Human TXNDC17 Recombinant Protein (RPPB5052)
- SKU:
- RPPB5052
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9BRA2
Description
| Product Name: | Human TXNDC17 Recombinant Protein |
| Product Code: | RPPB5052 |
| Size: | 20µg |
| Species: | Human |
| Target: | TXNDC17 |
| Synonyms: | Thioredoxin domain containing 17, Thioredoxin-like protein 5, Protein 42-9-9, thioredoxin (Trx)-related protein 14 kDa, TRP14, TXNL5, MGC14353. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The TXNDC17 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 50mM Nacl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMARYEE VSVSGFEEFH RAVEQHNGKT IFAYFTGSKD AGGKSWCPDC VQAEPVVREG LKHISEGCVF IYCQVGEKPY WKDPNNDFRK NLKVTAVPTL LKYGTPQKLV ESECLQANLV EMLFSED |
TXNDC17 is a disulfide reductase that takes part in several redox reactions using the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. TXNDC17 has peroxidase activity and assists to eliminate cellular hydrogen peroxide.
TXNDC17 Human Recombinant produced in E. coli is a single polypeptide chain containing 147 amino acids (1-123) and having a molecular mass of 16.5kDa.TXNDC17 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9BRA2 |
| NCBI GenInfo Identifier: | 14249348 |
| NCBI Gene ID: | 84817 |
| NCBI Accession: | NP_116120.1 |
| UniProt Secondary Accession: | Q9BRA2,A8K7E8 |
| UniProt Related Accession: | Q9BRA2 |
| Molecular Weight: | 13,941 Da |
| NCBI Full Name: | thioredoxin domain-containing protein 17 |
| NCBI Synonym Full Names: | thioredoxin domain containing 17 |
| NCBI Official Symbol: | TXNDC17�� |
| NCBI Official Synonym Symbols: | TRP14; TXNL5�� |
| NCBI Protein Information: | thioredoxin domain-containing protein 17 |
| UniProt Protein Name: | Thioredoxin domain-containing protein 17 |
| UniProt Synonym Protein Names: | 14 kDa thioredoxin-related protein; TRP14; Protein 42-9-9; Thioredoxin-like protein 5 |
| Protein Family: | |
| UniProt Gene Name: | TXNDC17�� |
| UniProt Entry Name: |
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