Human TWEAK / TNFSF12 ELISA Kit

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SKU:
HUFI02931
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O43508
Sensitivity:
18.75pg/ml
Range:
31.2-2000pg/ml
ELISA Type:
Sandwich
Synonyms:
TWEAK, TNFSF12, APO3 ligand, APO3LMGC20669, DR3LGTWEAKAPO3, DR3 ligand, MGC129581, TNF-related weak inducer of apoptosis, tumor necrosis factor, ligand superfamily, member 12, tumor necrosis factor ligand superfamily member 12
Reactivity:
Human
Research Area:
Cardiovascular

Description

Human TWEAK / TNFSF12 ELISA Kit

TWEAK / TNFSF12 ia a ongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue dist is a cytokine that belribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]

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