Human TSHR Full-Length Bioactive Membrane Protein (HDFP026)

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SKU:
HDFP026
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
P16473

Description

system_update_altDatasheet
Product nameHuman TSHR full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP026
Product CategoryFull Length Transmembrane Proteins
Target:TSHR
Uniprot:P16473
Description:Human TSHR full length protein-synthetic nanodisc
Molecular Weight:The human full length TSHR protein has a MW of 86.8 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:Autoimmune thyroid disease, Neuroactive ligand-receptor interaction
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:CHNG1; hTSHR-I; LGR3
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:The protein is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism.
Delivery:In Stock
UsageResearch use only
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