Epigenetics & Nuclear Signaling Recombinant Proteins
Human TSC22D1 Recombinant Protein (RPES4821)
- SKU:
- RPES4821
Description
Human TSC22D1 Recombinant Protein
TSC22 domain family, member 1 (TSC22D1) is one of the TGF-beta-stimulated clone-22 (TSC-22). TSC-22 was reported to be a differentiation-inducing factor which negatively regulates the growth of salivary gland cancer cells. TSC22D1, which encodes transforming growth factor beta-stimulated clone 22 (TSC-22), is thought to be a tumor suppressor because its expression is lost in many glioblastoma, salivary gland, and prostate cancers. TSC-22 is the founding member of the TSC-22/DIP/Bun family of leucine zipper transcription factors. TSC-22 may play an important role in maintaining the differentiated phenotype in salivary gland tumors, and may be a possible target of leukemia therapy. TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity.
| Product Name: | Human TSC22D1 Recombinant Protein (RPES4821) |
| Product Code: | RPES4821 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Ptg-2,TGFB1I4,TSC22 |
| Accession: | Q15714-2 |
| Sequence: | Met 1-Ala 144 |
| Fusion tag: | N-His |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the human TSC22D1 isoform 2 (Q15714-2) (Met 1-Ala 144) was expressed, with a polyhistidine tag at the N-terminus. |
| Purity: | > 92 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 17.2 kDa |
| AP Mol Mass: | 20 kDa |
| Formulation: | Lyophilized from sterile PBS, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Epigenetics & Nuclear Signaling |
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