Epigenetics & Nuclear Signaling Recombinant Proteins

Human TSC22D1 Recombinant Protein (RPES4821)

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SKU:
RPES4821
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Epigenetics & Nuclear Signaling

Description

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Human TSC22D1 Recombinant Protein

TSC22 domain family, member 1 (TSC22D1) is one of the TGF-beta-stimulated clone-22 (TSC-22). TSC-22 was reported to be a differentiation-inducing factor which negatively regulates the growth of salivary gland cancer cells. TSC22D1, which encodes transforming growth factor beta-stimulated clone 22 (TSC-22), is thought to be a tumor suppressor because its expression is lost in many glioblastoma, salivary gland, and prostate cancers. TSC-22 is the founding member of the TSC-22/DIP/Bun family of leucine zipper transcription factors. TSC-22 may play an important role in maintaining the differentiated phenotype in salivary gland tumors, and may be a possible target of leukemia therapy. TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity.

Product Name:Human TSC22D1 Recombinant Protein (RPES4821)
Product Code:RPES4821
Size:20µg
Species:Human
Expressed Host:E.coli
Synonyms:Ptg-2,TGFB1I4,TSC22
Accession:Q15714-2
Sequence:Met 1-Ala 144
Fusion tag:N-His
Endotoxin:Please contact us for more information.
Protein Construction:A DNA sequence encoding the human TSC22D1 isoform 2 (Q15714-2) (Met 1-Ala 144) was expressed, with a polyhistidine tag at the N-terminus.
Purity:> 92 % as determined by reducing SDS-PAGE.
Mol Mass:17.2 kDa
AP Mol Mass:20 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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