Human Tryptase B-2/TPSB2 Recombinant Protein (RPES1487)

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SKU:
RPES1487
Product Type:
Recombinant Protein
Species:
Human

Description

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Human Tryptase B-2/TPSB2 Recombinant Protein

Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.

Product Name:Human Tryptase B-2/TPSB2 Recombinant Protein (RPES1487)
Product Code:RPES1487
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Tryptase Beta-2, Tryptase-2, Tryptase II, TPSB2, TPS2
Accession:P20231
Sequence:Ala19-Pro275
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Tryptase beta-2 is produced by our Mammalian expression system and the target gene encoding Ala19-Pro275 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:29.6 kDa
AP Mol Mass:30 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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