Human Trypsin 2 / PRSS2 ELISA Kit

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SKU:
HUFI00569
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P07478
Sensitivity:
0.469ng/ml
Range:
0.781-50ng/ml
ELISA Type:
Sandwich
Synonyms:
PRSS2, Protease, Serine, 2, Tesp4, TRY8, TRY2, TRY8, TRYP2, trypsin 2, Trypsin II, trypsin-2, trypsinogen 2, Trypsinogen 20, Anionic trypsinogen, protease serine 2 preproprotein, Serine protease 2
Reactivity:
Human
Research Area:
Cell Biology

Description

Human Trypsin 2 / PRSS2 ELISA Kit

Trypsin 2 / PRSS2 belongs to the trypsin family of serine proteases and encodes an anionic trypsinogen. Trypsin 2 / PRSS2 is found in high levels in the pancreas and cleaves peptide bonds that follow lysine or arginine residues. Upregulation of Trypsin 2 / PRSS2 is a characteristic feature of pancreatitis. Trypsin 2 / PRSS2 is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Trypsin 2 / PRSS2 has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion.

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