Human Troponin C-I Recombinant Protein (RPPB5012)
- SKU:
- RPPB5012
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
| Product Name: | Human Troponin C-I Recombinant Protein |
| Product Code: | RPPB5012 |
| Size: | 10µg |
| Species: | Human |
| Target: | Troponin C-I |
| Synonyms: | Troponin I cardiac muscle, Cardiac troponin I, TNNI3, TNNC1, CMH7, RCM1, cTnI, CMD2A, MGC116817, Troponin C slow skeletal and cardiac muscles, TN-C, TNNC1, TNNC, TNC, CMD1Z. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colourless liquid formualtion. |
| Formulation: | Human Cardiac Troponin C-I� complex�solution contains 500 mM Nacl, 20mM Tris-HCl and 60 mM B-mercaptoethanol, pH 7.5. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by Analysis by SDS-PAGE. |
Troponin Complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, Troponin I, Troponin T and TroponinC. Each subunit is responsible for part of Troponin Complex function. E.g. Troponin I inhibits ATP-ase activity of acto-myosin.Troponin T and Troponin Iare presented in cardiac muscles in different forms than in skeletal muscles. Purified subunits of rcTnI, rcTnC and rcTnT are recomplexed in vitro under appropriate conditions.
Recombinant Human Cardiac Troponin C-I complex produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of approximately 50kDa. The Molar ratio on cTnC to cTnI is 1:1.The Cardiac Troponin C-I is purified by proprietary chromatographic techniques.
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