Signal Transduction Recombinant Proteins
Human TROP2/TACSTD2 Recombinant Protein (RPES3941)
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- SKU:
- RPES3941
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Signal Transduction
Description
system_update_altDatasheet
Human TROP2/TACSTD2 Recombinant Protein
Tumor associated calcium signal transducer 2 (TACSTD2; TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
| Product Name: | Human TROP2/TACSTD2 Recombinant Protein (RPES3941) |
| Product Code: | RPES3941 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Tumor-associated calcium signal transducer 2,Membrane component chromosome 1 surface marker 1,Cell surface glycoprotein Trop-2, TACSTD2,TROP2 |
| Accession: | P09758 |
| Sequence: | Thr88-Thr274 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human TROP2 is produced by our Mammalian expression system and the target gene encoding Thr88-Thr274 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 22.6 kDa |
| AP Mol Mass: | 28-40 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; 5%Trehalose; 2mM EDTA ; pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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