Human TRAPPC8 Recombinant Protein (His tag)

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SKU:
RPES5517
Product Type:
Recombinant Protein
Species:
Human

Description

Product Name:Human TRAPPC8 Recombinant Protein (His tag)
Product Code:RPES5517
Size:20µg
Species:Human
Expression Host:E.coli
Synonyms:Trafficking protein particle complex subunit 8, TRAPPC8, Protein TRS85 homolog, KIAA1012
Mol Mass:16.5 kDa
AP Mol Mass:20 kDa
Tag:N-His & C-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Gly 100-Gln 250
Accession:Q9Y2L5-1
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:The transport protein particle (TRAPP) complex was initially identified as a tethering factor for COPII vesicle. Subsequently, three forms (TRAPPI, II, and III) have been found and TRAPPIII has been reported to serve as a regulator in autophagy. This study investigates a new role of mammalian TRAPPIII in ciliogenesis. We found a ciliopathy protein, oral-facial-digital syndrome 1 (OFD1), interacting with the TRAPPIII-specific subunits TRAPPC8 and TRAPPC12. TRAPPC8 is necessary for the association of OFD1 with pericentriolar material 1 (PCM1).
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