Enzymes Recombinant Proteins

Human TPST2 Recombinant Protein (RPPB2347)

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SKU:
RPPB2347
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
O60704
Research Area:
Enzymes

Description

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Product Name:Human TPST2 Recombinant Protein
Product Code:RPPB2347
Size:10µg
Species:Human
Target:TPST2
Synonyms:Tyrosylprotein Sulfotransferase 2, EC 2.8.2.20, TPST-2,Transport And Golgi Organization 13 Homolog B (Drosophila), Transport And GolgiOrganization 13 Homolog B, Protein-Tyrosine Sulfotransferase 2, TyrosylproteinPhosphotransferase 2, Tyrosylprotein Sulfotransferase-2, TANGO13B.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered colorless solution.
Formulation:TPST2 protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).�Avoid multiple freeze-thaw cycles.
Purity:Greaterthan 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:ADPQQVLECR AVLAGLRSPR GAMRPEQEEL VMVGTNHVEY RYGKAMPLIFVGGVPRSGTT LMRAMLDAHP EVRCGEETRI IPRVLAMRQA WSKSGREKLR LDEAGVTDEV LDAAMQAFILEVIAKHGEPA RVLCNKDPFT LKSSVYLSRL FPNSKFLLMV RDGRASVHSM ITRKVTIAGF DLSSYRDCLTKWNKAIEVMY AQCMEVGKEK CLPVYYEQLV LHPRRSLKLI LDFLGIAWSD AVLHHEDLIG KPGGVSLSKIERSTDQVIKP VNLEALSKWT GHIPGDVVRD MAQIAPMLAQ LGYDPYANPP NYGNPDPFVI NNTQRVLKGDYKTPANLKGY FQVNQNSTSS HLGSSHHHHH H

Tyrosylprotein Sulfotransferase 2 (TPST2) is a member of the protein sulfotransferase family. TPST2 is a widely expressed protein, which catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The TPST2 protein is a type II integral membrane protein located in the Golgi body.

TPST2 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 361 amino acids (26-377 a.a.) andhaving a molecular mass of 40.4kDa (Migrates at 40-57kDa on SDS-PAGE underreducing conditions).�TPST2 is expressed with a 6amino acid His tag at C-Terminus and purified by proprietary chromatographictechniques.

UniProt Protein Function:TPST2: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides. Belongs to the protein sulfotransferase family.
UniProt Protein Details:

Protein type:EC 2.8.2.20; Endoplasmic reticulum; Membrane protein, integral; Transferase

Chromosomal Location of Human Ortholog: 22q12.1

Cellular Component: Golgi membrane; membrane; endoplasmic reticulum; integral to membrane

Molecular Function:protein-tyrosine sulfotransferase activity

Biological Process: fusion of sperm to egg plasma membrane; peptidyl-tyrosine sulfation

NCBI Summary:The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:O60704
NCBI GenInfo Identifier:6686027
NCBI Gene ID:8459
NCBI Accession:O60704.1
UniProt Secondary Accession:O60704,Q6FI98, Q9H0V4, B3KQA7,
UniProt Related Accession:O60704
Molecular Weight:377
NCBI Full Name:Protein-tyrosine sulfotransferase 2
NCBI Synonym Full Names:tyrosylprotein sulfotransferase 2
NCBI Official Symbol:TPST2��
NCBI Official Synonym Symbols:TANGO13B��
NCBI Protein Information:protein-tyrosine sulfotransferase 2; TPST-2; tyrosylprotein sulfotransferase-2; tyrosylprotein phosphotransferase 2; transport and golgi organization 13 homolog B
UniProt Protein Name:Protein-tyrosine sulfotransferase 2
UniProt Synonym Protein Names:Tyrosylprotein sulfotransferase 2; TPST-2
Protein Family:Protein-tyrosine sulfotransferase
UniProt Gene Name:TPST2��
UniProt Entry Name:TPST2_HUMAN
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