Human TPBG/5T4 Recombinant Protein (RPES4169)
- SKU:
- RPES4169
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human TPBG/5T4 Recombinant Protein
Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
| Product Name: | Human TPBG/5T4 Recombinant Protein (RPES4169) |
| Product Code: | RPES4169 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | 5T4 Protein, Human,5T4AG Protein, Human,M6P1 Protein, Human,WAIF1 Protein, Human |
| Accession: | Q13641 |
| Sequence: | Ser32-Ser355 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human TPBG is produced by our Mammalian expression system and the target gene encoding Ser32-Ser355 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 36.1 kDa |
| AP Mol Mass: | 55-80 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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