Tumor necrosis factor receptor superfamily member 1B is a 461 amino acids protein that belongs to the TNFR (tumor necrosis factor receptor) superfamily characterized by cysteine-rich extracellular domains. It contains 4 TNFR-Cys repeats. TNFRII is expressed in fetal brain. TNFRII is strongly expressed at the cartilage-pannus junction; and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA). This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis; which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Product Name:
Human TNFRSF1B/CD120b Recombinant Protein (RPES4098)
Product Code:
RPES4098
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor type II, p75, p80 TNF-alpha receptor, TBP-2, TBPII, TNFRSF1B, TNFBR, TNFR2, Tumor Necrosis Factor Receptor II
Accession:
P20333
Sequence:
Leu23-Asp257
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human TNFRSF1B is produced by our Mammalian expression system and the target gene encoding Leu23-Asp257 is expressed with a 6His tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
26.2 kDa
AP Mol Mass:
40 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
system_update_altDatasheetHuman TNFRSF1B/CD120b Recombinant Protein Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily.
system_update_altDatasheetHuman TNFRSF1B/CD120b Recombinant Protein Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD1
system_update_altDatasheetHuman TNFRSF1B/CD120b Recombinant Protein Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD1
system_update_altDatasheetHuman TNFRSF1B/CD120b Recombinant Protein Tumor necrosis factor receptor superfamily member 1B(TNFRSF1B) is expressed by the gene TNFRSF1B. The soluble form is produced
system_update_altDatasheetHuman TNFRSF1B/CD120b Recombinant Protein Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD1
system_update_altDatasheetHuman TNFRSF1B/CD120b Recombinant Protein Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily.
system_update_altDatasheetMouse TNFRSF1B/CD120b Recombinant Protein Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD1
system_update_altDatasheetMouse TNFRSF1B/CD120b Recombinant Protein Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD1