Immune Checkpoint Recombinant Proteins
Human TNFRSF10B Recombinant Protein (mFc Tag) (HDPT0079)
- SKU:
- HDPT0079
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human TNFRSF10B Recombinant Protein (mFc Tag)
Description: | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
Product name: | Human TNFRSF10B Recombinant Protein (mFc Tag) |
Synonyms: | TNFRSF10B,TRAILR2,TRAIL-R2,CD262,DR5,KILLER,TRICK2,ZTNFR9,TRICKB |
Type: | protein |
Size: | 50 µg |
Name: | TNFRSF10B |
Origin: | Human |
Source: | HEK293 |
Protein Type: | Recombinant |
Application: | Contact Technical Support |
Purity: | > 95% |
Purification: | affinity purification |
Format: | Lyophilized |
Conjugate: | C-Mouse Fc tag |
Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
Usage: | Research use only |
Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
Reconstitution: | Reconstitute with deionized water |
Sequence: | TNFRSF10B (Ile56-Glu186)+mFc(Pro99-Lys330) |
Gene ID: | 8795 |
Uniprot: | O14763 |
Molecular Weight: | 40.5 kDa |