Immune Checkpoint Recombinant Proteins

Human TNFα Recombinant Protein (His Tag) (HDPT0060)

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SKU:: HDPT0060
UPC:
MPN:
Product Type:: Recombinant Protein
Species:: Human
Research Area:: Immune Checkpoint

Description
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Description

Human TNFα Recombinant Protein (His Tag)

Description:	This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Product name:	Human TNFα Recombinant Protein (His Tag)
Synonyms:	DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα
Type:	protein
Size:	50 µg
Name:	TNFα
Origin:	Human
Source:	HEK293
Protein Type:	Recombinant
Application:	Contact Technical Support
Purity:	> 95%
Purification:	affinity purification
Format:	Lyophilized
Conjugate:	C-6×His tag
Storage:	Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:	Research use only
Buffer:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:	Reconstitute with deionized water
Sequence:	TNFα（Val77-Leu233）+6×His tag
Gene ID:	7124
Uniprot:	P01375
Molecular Weight:	18.1 kDa