Immune Checkpoint Recombinant Proteins

Human TMEM173 Recombinant Protein (hFc Tag) (HDPT0189)

(No reviews yet) Write a Review
SKU:
HDPT0189
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human TMEM173 Recombinant Protein (hFc Tag)

Description:This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Product name:Human TMEM173 Recombinant Protein (hFc Tag)
Synonyms:ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING, STING-beta, TMEM173
Type:protein
Size:50 µg
Name:TMEM173
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 90%
Purification:affinity purification
Format:Lyophilized
Conjugate:N-Human Fc tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:hFc(Glu99-Ala330)+TMEM173 (Leu139-Ser379)
Gene ID:340061
Uniprot:Q86WV6
Molecular Weight:53.2 kDa
View AllClose

0 Reviews

View AllClose