Human TLR5 / Toll-like receptor 5 ELISA Kit

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SKU:
HUFI01708
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O60602
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
TLR5, Toll-like receptor 5, TIL3, SLEB1, Toll, interleukin-1 receptor-like protein 3, TIL-3, TIL3Toll, interleukin-1 receptor-like protein 3, toll-like receptor 5
Reactivity:
Human
Research Area:
Immunology

Description

Human TLR5 / Toll-like receptor 5 ELISA

TLR5 / Toll-like receptor 5 plays a fundamental role in pathogen recognition and activation of innate immune responses. TLR5 / Toll-like receptor 5 recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of TLR5 / Toll-like receptor 5 mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in TLR5 / Toll-like receptor 5 have been associated with susceptibility to Legionnaire disease and systemic lupus erythematosus.

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