Cardiovascular Recombinant Proteins
Human Tissue Factor/CD142 Recombinant Protein (RPES0751)
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- SKU:
- RPES0751
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cardiovascular
Description
system_update_altDatasheet
Human Tissue Factor/CD142 Recombinant Protein
Tissue Factor (TF) is a single-pass type I membrane glycoprotein member of the tissue factor family. TF expression is highly dependent upon cell type. This factor enables cells to initiate the blood coagulation cascades; and it functions as the high-affinity receptor for the coagulation factor VII. TF initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
| Product Name: | Human Tissue Factor/CD142 Recombinant Protein (RPES0751) |
| Product Code: | RPES0751 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Tissue Factor, TF, Coagulation Factor III, Thromboplastin, CD142, F3, TFA, coagulation factor 3 |
| Accession: | P13726 |
| Sequence: | Gly34-Glu251 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Coagulation Factor III/Tissue Factor is produced by our Mammalian expression system and the target gene encoding Gly34-Glu251 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 25.8 kDa |
| AP Mol Mass: | 69 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.2. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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