Immune Checkpoint Recombinant Proteins
Human TIM3 Recombinant Protein (mFc-His Tag) (HDPT0030)
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- SKU:
- HDPT0030
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human TIM3 Recombinant Protein (mFc-His Tag)
| Description: | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
| Product name: | Human TIM3 Recombinant Protein (mFc-His Tag) |
| Synonyms: | HAVCR2, TIM3, TIMD3, FLJ14428, KIM3 |
| Type: | protein |
| Size: | 50 µg |
| Name: | TIM3 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | ELISA |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Mouse Fc and 6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | TIM3（Ser22-Gly202）+mFc（Pro99-Lys330）+6×His tag |
| Gene ID: | 84868 |
| Uniprot: | Q8TDQ0 |
| Molecular Weight: | 47.5 kDa |
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