Human THOP1 / Thimet oligopeptidase ELISA Kit

(No reviews yet) Write a Review
SKU:
HUFI01197
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P52888
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
THOP1, Thimet oligopeptidase
Reactivity:
Human
Research Area:
Cell Biology

Description

Human THOP1 / Thimet oligopeptidase ELISA Kit

THOP1/Thimet oligopeptidase, which is a homologue of the CD13 antigen, has been shown to be expressed on human myeloid leukaemia cells and has been suggested as a target for antibody-based therapies. THOP1 is a kininase that uses zinc as a cofactor. THOP1 cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. Diseases associated with THOP1 include Infantile Spasms and Mental Retardation X-Linked Type 3. Clathrin derived vesicle budding and Vesicle-mediated transport are pathways liked to THOP1/Thimet oligopeptidase.

View AllClose

0 Reviews

View AllClose