Human THOP1 Recombinant Protein (RPES0647)
- SKU:
- RPES0647
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human THOP1 Recombinant Protein
Thimet oligopeptidase, a homologue of the CD13 antigen, has been identified in human myeloid leukaemia cells and is considered a potential target for antibody-based therapies. THOP1 is a kininase that uses zinc as a cofactor. Cytosolic peptides are broken down by THOP1, making them unavailable to antigen-presenting cells. Infantile spasms and mental retardation X-linked type 3 are two examples of THOP1-related disorders. THOP1/Thimet oligopeptidase is involved in clathrin-derived vesicle budding and Vesicle-mediated transport. Human THOP1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human THOP1 Recombinant Protein (RPES0647) |
| Product Code: | RPES0647 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Thimet Oligopeptidase, Endopeptidase 24.15, MP78, THOP1 |
| Accession: | P52888 |
| Sequence: | Lys2-Cys689 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Thimet Oligopeptidase is produced by our E.coli expression system and the target gene encoding Lys2-Cys689 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 80.0 kDa |
| AP Mol Mass: | 85 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM PB, 100mM NaCl, 10% Glycerol, pH 7.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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