Cell Biology Recombinant Proteins
Human Thioredoxin-2/TXN2 Recombinant Protein (RPES0719)
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- SKU:
- RPES0719
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Biology
Description
system_update_altDatasheet
Human Thioredoxin-2/TXN2 Recombinant Protein
Thioredoxin-2 (TXN2) is a mitochondrial member of the thioredoxin family. Thioredoxin-2 is extensively expressed in adult and fetal tissues. Thioredoxin-2 contains an N-terminal 59 amino acid transit peptide; which is cleaved before translocating to mitochondria. Mitochondrial thioredoxin play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Thioredoxin-2 could be involved in the resistance to anti-tumor agents and possesses a dithiol-reducing activity. In addition; Thioredoxin-2 is important at low oxidative stress conditions.
| Product Name: | Human Thioredoxin-2/TXN2 Recombinant Protein (RPES0719) |
| Product Code: | RPES0719 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Thioredoxin Mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2 |
| Accession: | Q99757 |
| Sequence: | Thr60-Gly166 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Thioredoxin-2 is produced by our E.coli expression system and the target gene encoding Thr60-Gly166 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 12.0 kDa |
| AP Mol Mass: | 13 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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