Growth Factors & Cytokines Recombinant Proteins
Human TGFB1/TGF-beta 1 Recombinant Protein (RPES1385)
- SKU:
- RPES1385
Description
Human TGFB1/TGF-beta 1 Recombinant Protein
Transforming Growth Factor beta-1 (TGF beta-1) is a secreted protein which belongs to the TGF-beta family. TGF beta-1 is found in high amounts in bone, especially in articular cartilage and chondrocytes. It's also higher in osteoarthritis (OA). TGF beta-1 controls cell growth, proliferation, differentiation, as well as apoptosis in a variety of cells. The precursor is cleaved into a latency-associated peptide (LAP) and a fully processed TGF beta-1 protein. TGF-beta may also interact with other TGF beta family members, forming heterodimers. TGF beta-1 is upregulated in tumor cells, according to studies. Camurati-Engelmann disease is a genetic condition that results from mutations in the TGF beta-1 gene. Human TGFB1/TGF-beta 1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human TGFB1/TGF-beta 1 Recombinant Protein (RPES1385) |
| Product Code: | RPES1385 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Transforming Growth Factor Beta-1, TGF-Beta-1, Latency-Associated Peptide, LAP, TGFB1, TGFB,CED,DPD1,TGF-beta 1 |
| Accession: | P01137 |
| Sequence: | Ala279-Ser390 |
| Fusion tag: | |
| Activity: | Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells. The ED50 for this effect is 0.04-0.2 ng/ml |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 12.8 kDa |
| AP Mol Mass: | 13 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 50mM Glycine; 50mM NaCl; pH4.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Growth Factors & Cytokines |
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Growth Factors & Cytokines Recombinant Proteins