Immunology Recombinant Proteins

Human Tetherin/BST2 Recombinant Protein (RPES1415)

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SKU:
RPES1415
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology

Description

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Human Tetherin/BST2 Recombinant Protein

Bone Marrow Stromal Antigen 2 (BST2) is a single-pass type II membrane protein that belongs to the tetherin family. BST2 is predominantly expressed in the liver; lung; heart and placenta. BST2 is involved in the sorting of secreted proteins. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. BST2 is initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu; it has also been shown to inhibit the release of other viruses such as retroviruses; filoviruses; arenaviruses; and herpes viruses. BST2 may play a role in B-cell activation in rheumatoid arthritis.

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