Immunology Recombinant Proteins

Human Tetherin/BST2 Recombinant Protein (RPES0108)

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SKU:
RPES0108
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology

Description

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Human Tetherin/BST2 Recombinant Protein

CLM-9; also known as TREM4; is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils; monocyte/macrophages; microglia; and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart; skeletal muscle; and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.

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