Immunology Recombinant Proteins

Human Tetherin/BST2 Recombinant Protein (RPES0108)

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RPES0108

Description

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Human Tetherin/BST2 Recombinant Protein

CLM-9; also known as TREM4; is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils; monocyte/macrophages; microglia; and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart; skeletal muscle; and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.

Product Name:Human Tetherin/BST2 Recombinant Protein (RPES0108)
Product Code:RPES0108
Size:20µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:Bone Marrow Stromal Antigen 2, BST-2, HM1.24 Antigen, Tetherin, CD317, BST2
Accession:Q10589
Sequence:Asn49-Ser160
Fusion tag:N-Fc
Endotoxin:<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human BST2 (Q10589) (Asn49-Ser160) was expressed;with the fused Fc region of human IgG1 at the N-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:41 kDa
AP Mol Mass:51 kDa
Formulation:Lyophilized from sterile PBS; pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology
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