Human TCEAL1 Recombinant Protein (RPPB4922)

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SKU:
RPPB4922
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q15170

Description

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Product Name:Human TCEAL1 Recombinant Protein
Product Code:RPPB4922
Size:20µg
Species:Human
Target:TCEAL1
Synonyms:Transcription elongation factor A protein-like 1, TCEA-like protein 1, Nuclear phosphoprotein p21/SIIR, Transcription elongation factor S-II protein-like 1, TCEAL1, SIIR, p21, pp21.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The TCEAL1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 20% glycerol and 0.1M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MDKPRKENEE EPQSAPKTDE ERPPVEHSPE KQSPEEQSSE EQSSEEEFFP EELLPELLPE MLLSEERPPQ EGLSRKDLFE GRPPMEQPPC GVGKHKLEEG SFKERLARSR PQFRGDIHGR NLSNEEMIQA ADELEEMKRV RNKLMIMHWK AKRSRPYPIL EHHHHHH

Transcription elongation factor A protein-like 1 (TCEAL1) is a member of the transcription elongation factor A (SII)-like (TCEAL) family, which may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. TCEAL1 is involved in transcriptional regulation. TCEAL1 is expressed in all tissues, especially highly expressed in the heart, ovary, prostate and skeletal muscle.

TCEAL1 Human Recombinant fused with an 8 amino acid His tag at C-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 167 amino acids (1-159 a.a.) and having a molecular mass of 19.7kDa. The TCEAL1 is purified by proprietary chromatographic techniques.

UniProt Protein Function:May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.
UniProt Protein Details:
NCBI Summary:This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
UniProt Code:Q15170
NCBI GenInfo Identifier:108935936
NCBI Gene ID:9338
NCBI Accession:Q15170.2
UniProt Secondary Accession:Q15170,Q9UJQ9
UniProt Related Accession:Q15170
Molecular Weight:
NCBI Full Name:Transcription elongation factor A protein-like 1
NCBI Synonym Full Names:transcription elongation factor A like 1
NCBI Official Symbol:TCEAL1��
NCBI Official Synonym Symbols:p21; SIIR; WEX9; pp21��
NCBI Protein Information:transcription elongation factor A protein-like 1
UniProt Protein Name:Transcription elongation factor A protein-like 1
UniProt Synonym Protein Names:Nuclear phosphoprotein p21/SIIR; Transcription elongation factor S-II protein-like 1
Protein Family:Transcription elongation factor A protein
UniProt Gene Name:TCEAL1��
UniProt Entry Name:TCAL1_HUMAN
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