Human TCblR/8D6A Recombinant Protein (RPES1135)
- SKU:
- RPES1135
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human TCblR/8D6A Recombinant Protein
CD320 antigen is also known as 8D6 antigen?FDC-signaling molecule 8D6?Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.
| Product Name: | Human TCblR/8D6A Recombinant Protein (RPES1135) |
| Product Code: | RPES1135 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | CD320 antigen,8D6 antigen,FDC-signaling molecule 8D6,FDC-SM-8D6,Transcobalamin receptor,TCblR,CD320 |
| Accession: | Q9NPF0 |
| Sequence: | Ser36-Val231 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Transcobalamin II Receptor is produced by our Mammalian expression system and the target gene encoding Ser36-Val231 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 21.1 kDa |
| AP Mol Mass: | 43 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 10mM Tris-Citrate,150mM NaCl, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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