Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. In the apo state, BIRC5 exists as a homodimer and a monomer in the CPC-bound form. BIRC5 is a protein found only in the fetal kidneys and liver, to a lesser extent in the lung and brain. The BIRC5 protein has two functions: promoting cell proliferation and preventing apoptosis. The BIRC5 gene is a component of the chromosome passage protein complex (CPC), which is required for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex. Human Survivin/BIRC5 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Survivin/BIRC5 Recombinant Protein (RPES3302)
Recombinant Human Baculoviral IAP Repeat-Containing Protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Asp142 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
20.4 kDa
AP Mol Mass:
16 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM Tris, 0.1M NaCl, pH 7.5.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
