Cell Death Recombinant Proteins

Human STK24/MST3 Recombinant Protein (RPES0815)

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SKU:
RPES0815
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Death

Description

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Human STK24/MST3 Recombinant Protein

MST3 encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants.

Product Name:Human STK24/MST3 Recombinant Protein (RPES0815)
Product Code:RPES0815
Size:20µg
Species:Human
Expressed Host:Baculovirus-Insect Cells
Synonyms:HEL-S-95,MST3,MST3B,RP11-111L24.5,STE20,STK3
Accession:Q9Y6E0-2
Sequence:Met 1-His 431
Fusion tag:N-His
Activity:The specific activity was determined to be 62 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human STK24 isoform A (Q9Y6E0-2) (Met 1-His 431) was expressed, with a polyhistidine tag at the N-terminus.
Purity:> 82 % as determined by reducing SDS-PAGE.
Mol Mass:50.3 kDa
AP Mol Mass:55 kDa
Formulation:Supplied as sterile 50mM Tris, 100mM NaCl, pH 8.0, 20% gly, 0.1mM EGTA, 0.1mM EDTA, 0.25mM DTT
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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