Description
| Product Name: | Human STK16 Recombinant Protein |
| Product Code: | RPPB2652 |
| Size: | 20µg |
| Species: | Human |
| Target: | STK16 |
| Synonyms: | Serine/threonine-protein kinase 16, Myristoylated and palmitoylated serine/threonine-protein kinase, MPSK, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, Tyrosine-protein kinase STK16, hPSK, STK16, MPSK1, PKL12, TSF1, KRCT. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | STK16 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMGHALC VCSRGTVIID NKRYLFIQKL GEGGFSYVDL VEGLHDGHFY ALKRILCHEQ QDREEAQREA DMHRLFNHPN ILRLVAYCLR ERGAKHEAWL LLPFFKRGTL WNEIERLKDK GNFLTEDQIL WLLLGICRGL EAIHAKGYAH RDLKPTNILL GDEGQPVLMD LGSMNQACIH VEGSRQALTL QDWAAQRCTI SYRAPELFSV QSHCVIDERT DVWSLGCVLY AMMFGEGPYD MVFQKGDSVA LAVQNQLSIP QSPRHSSALR QLLNSMMTVD PHQRPHIPLL LSQLEALQPP APGQHTTQI |
Serine/threonine-protein kinase 16 (STK16) is a membrane-associated protein kinase which phosphorylates on serine and threonine residues. STK16 is involved in secretory vesicle trafficking or intracellular signaling. Furthermore, the STK16 protein may have a role in regulating stromal-epithelial interactions which occur during ductal morphogenesis in the mammary gland. STK16 can autophosphorylate on Tyr residue; it is however unclear whether STK16 has tyrosine-protein kinase toward other proteins. STK16 may also be involved in TGF-beta signaling.
STK16 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 329 amino acids (1-305 a.a) and having a molecular mass of 37.2kDa.STK16 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | MPSK1: a protein kinase of the STE20 family. Activated by caspase-mediated cleavage |
| UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; EC 2.7.11.1; EC 2.7.10.2; Other group; NAK family Chromosomal Location of Human Ortholog: 2q35 Cellular Component: cytoplasm Molecular Function:protein binding; protein serine/threonine kinase activity Biological Process: protein amino acid autophosphorylation |
| UniProt Code: | O75716 |
| NCBI GenInfo Identifier: | 46577677 |
| NCBI Gene ID: | 8576 |
| NCBI Accession: | O75716.4 |
| UniProt Secondary Accession: | O75716,Q5U0F8, Q96KI2, Q9BUH4, Q9UEN3, Q9UP78, A8K9H9 |
| UniProt Related Accession: | O75716 |
| Molecular Weight: | 34,656 Da |
| NCBI Full Name: | Serine/threonine-protein kinase 16 |
| NCBI Synonym Full Names: | serine/threonine kinase 16 |
| NCBI Official Symbol: | STK16�� |
| NCBI Official Synonym Symbols: | KRCT; MPSK; TSF1; PKL12�� |
| NCBI Protein Information: | serine/threonine-protein kinase 16 |
| UniProt Protein Name: | Serine/threonine-protein kinase 16 |
| UniProt Synonym Protein Names: | Myristoylated and palmitoylated serine/threonine-protein kinase; MPSK; Protein kinase PKL12; TGF-beta-stimulated factor 1; TSF-1; Tyrosine-protein kinase STK16 (EC:2.7.10.2); hPSK |
| Protein Family: | Serine/threonine-protein kinase |
| UniProt Gene Name: | STK16�� |
| UniProt Entry Name: | STK16_HUMAN |
