Human STEAP1 Full-Length Bioactive Membrane Protein (HDFP051)

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SKU:
HDFP051
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
Q9UHE8

Description

system_update_altDatasheet
Product nameHuman STEAP1 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP051
Product CategoryFull Length Transmembrane Proteins
Target:STEAP1
Uniprot:Q9UHE8
Description:Human STEAP1 full length protein-synthetic nanodisc
Molecular Weight:The human full length STEAP1 protein has a MW of 39.9 kDa
Protein Family:Transmembrane
Protein Pathways:
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:PRSS24; STEAP
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:STEAP1 is a cell-surface biomolecule composed by sixtransmembrane domains connected by intra- and extracellular loops. It is commonly found overexpressed in several types of cancers, namely in PCa, and is preferentially located at the tight or gap junctions. However, in nontumoural tissues and vital organs, STEAP1 protein presents low or absent expression, unveiling considerable specificity for cancer environment. Taking into account STEAP1 predicted transmembrane topology and cellular localization, it has been hypothesized that STEAP1 may play an important role as a transporter protein and can be involved in intercellular communication. 
Delivery:In Stock
UsageResearch use only
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