Human STC2 / Stanniocalcin-2 ELISA Kit

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SKU:
HUFI01124
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O76061
Sensitivity:
18.75pg/ml
Range:
31.25-2000pg/ml
ELISA Type:
Sandwich
Synonyms:
STC2, Stanniocalcin-2, STC-2, Stanniocalcin-related protein, STC-related protein, STCRP
Reactivity:
Human
Research Area:
Cell Biology

Description

Human STC2 / Stanniocalcin-2 ELISA Kit

STC2/Stanniocalcin-2 is a secreted homodimeric glycoprotein that is expressed in many tissues and may have autocrine or paracrine functions. The encoded protein shares 10 of its 15 cysteine residues with other members of the stanniocalcin family and is phosphorylated exclusively on its serine residues by casein kinase 2. STC2/Stanniocalcin-2 may be involved in the regulation of calcium and phosphate transport in the kidneys and intestines, as well as cell metabolism and cellular calcium/phosphate homeostasis. Prenatal and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly were all observed in mice with constitutive overexpression of human stanniocalcin 2. Estrogen stimulates the expression of this gene, which is altered in some breast cancers. Renal Cell Carcinoma and Nonpapillary Renal Cell Carcinoma are two diseases linked to STC2.

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