Immunology Recombinant Proteins
Human STAT3 Recombinant Protein (RPES5009)
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- SKU:
- RPES5009
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immunology
Description
system_update_altDatasheet
Human STAT3 Recombinant Protein
Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types. STAT3 is activated by multiple cytokines and growth factors including: IFN-a, IL-10, IL-6, IL-11, IL-12, IL-2, EGF etc. STAT3 functions as signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. In addition, STAT3 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
| Product Name: | Human STAT3 Recombinant Protein (RPES5009) |
| Product Code: | RPES5009 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Signal Transducer and Activator of Transcription 3, Acute-Phase Response Factor, STAT3, APRF |
| Accession: | P40763 |
| Sequence: | Met 1-Asn175 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Signal Transducer and Activator of Transcription 3 is produced by our E.coli expression system and the target gene encoding Met1-Asn175 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 21.8 kDa |
| AP Mol Mass: | 18 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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