Immunology Recombinant Proteins

Human STAT3 Recombinant Protein (RPES5009)

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SKU:
RPES5009
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology

Description

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Human STAT3 Recombinant Protein

Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types. STAT3 is activated by multiple cytokines and growth factors including: IFN-a, IL-10, IL-6, IL-11, IL-12, IL-2, EGF etc. STAT3 functions as signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. In addition, STAT3 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

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