Human SSB(Lupus La protein) ELISA Kit

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SKU:
HUFI03123
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P05455
Sensitivity:
18.75pg/ml
Range:
31.25-2000pg/ml
ELISA Type:
Sandwich
Synonyms:
Lupus La protein, Sjoegren syndrome type B antigen, SSB, La autoantigen, La ribonucleoprotein
Reactivity:
Human
Research Area:
Cell Biology

Description

Human SSB(Lupus La protein) ELISA Kit

SSB(Lupus La protein) is involved in diverse aspects of RNA metabolism, by acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB(Lupus La protein) binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. Autoantibodies reacting with SSB(Lupus La protein) are found in the serum of patients with Sjogren syndrome and systemic lupus erythematosus.

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