Human SRP19 Recombinant Protein (RPPB4828)
- SKU:
- RPPB4828
Description
| Product Name: | Human SRP19 Recombinant Protein |
| Product Code: | RPPB4828 |
| Size: | 10µg |
| Species: | Human |
| Target: | SRP19 |
| Synonyms: | Signal recognition particle 19kDa protein, SRP19. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The SRP19 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 50% glycerol and 2mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMACAAAR SPADQDRFIC IYPAYLNNKK TIAEGRRIPI SKAVENPTAT EIQDVCSAVG LNVFLEKNKM YSREWNRDVQ YRGRVRVQLK QEDGSLCLVQ FPSRKSVMLY AAEMIPKLKT RTQKTGGADQ SLQQGEGSKK GKGKKKK |
Signal recognition particle 19kDa protein (SRP19) is a member of the SRP19 family. SRP19 binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
SRP19 Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 167 amino acids (1-144 a.a.) and having a molecular mass of 18.5kDa. The SRP19 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SRP19: Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. Belongs to the SRP19 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 5q21-q22 Cellular Component: nucleoplasm; mitochondrion; cytoplasm; signal recognition particle, endoplasmic reticulum targeting; nucleolus; cytosol; nucleus Molecular Function:7S RNA binding Biological Process: response to drug; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; gene expression; cotranslational protein targeting to membrane |
| UniProt Code: | P09132 |
| NCBI GenInfo Identifier: | 115502457 |
| NCBI Gene ID: | 6728 |
| NCBI Accession: | P09132.3 |
| UniProt Secondary Accession: | P09132,Q05D77, Q96FG6, B2R4E9, D6RCQ5, |
| UniProt Related Accession: | P09132 |
| Molecular Weight: | 144 |
| NCBI Full Name: | Signal recognition particle 19 kDa protein |
| NCBI Synonym Full Names: | signal recognition particle 19kDa |
| NCBI Official Symbol: | SRP19�� |
| NCBI Protein Information: | signal recognition particle 19 kDa protein; signal recognition particle 19kD |
| UniProt Protein Name: | Signal recognition particle 19 kDa protein |
| Protein Family: | Signal recognition particle 19 kDa protein |
| UniProt Gene Name: | SRP19�� |
| UniProt Entry Name: | SRP19_HUMAN |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Uniprot: |
P09132 |
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