Human SPTAN1 / Alpha-Fodrin ELISA Kit

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SKU:
HUFI02870
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q13813
Sensitivity:
9.375pg/ml
Range:
15.625-1000pg/ml
ELISA Type:
Sandwich
Synonyms:
SPTAN1, Alpha-Fodrin
Reactivity:
Human
Research Area:
Cell Biology

Description

Human SPTAN1 / Alpha-Fodrin ELISA

SPTAN1 (Spectrin Alpha, Non-Erythrocytic 1) has been linked to a variety of cellular processes, including DNA repair and cell cycle control. Spectrins are a family of filamentous cytoskeletal proteins that serve as important scaffold molecules to help maintain the plasma membrane and organize intracellular organelles. Alpha and beta dimers come together in spectrins to form tetramers linked head-to-head. SPTAN1 mutations can cause developmental and epileptic encephalopathy 5 as well as West syndrome. RET signalling, apoptosis, and survival caspase cascade are all pathways influenced by the protein.

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