Human SPT beta N4 / Spectrin Beta, Non Erythrocytic 4 ELISA Kit

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SKU:
HUFI02871
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9H254
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
SPTBetaN4, Spectrin Beta, Non Erythrocytic 4
Reactivity:
Human

Description

Human SPT beta N4 / Spectrin Beta, Non Erythrocytic 4 ELISA

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton and regulates cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrin is made up of two antiparallel dimers of alpha- and beta-subunits. SPTBN4 (Spectrin Beta, Non-Erythrocytic 4) is part of the beta-spectrin gene family. SPTBN4 localizes to the nuclear matrix, PML nuclear bodies, and cell membrane vesicles. SPTBN4 disorder and neurodevelopmental conditions with hypotonia, neuropathy, and deafness are examples of diseases associated with SPTBN4. The RET pathway and cytokine signalling in the immune system are two pathways related to its role.

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