Human SOD2/Mn-SOD Recombinant Protein (RPES0098)
- SKU:
- RPES0098
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human SOD2/Mn-SOD Recombinant Protein
Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6); idiopathic cardiomyopathy (IDC); sporadic motor neuron disease; and cancer. SOD2 destroys superoxide anion radicals which are usually produced within the cells and which are toxic to biological systems.
| Product Name: | Human SOD2/Mn-SOD Recombinant Protein (RPES0098) |
| Product Code: | RPES0098 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Superoxide Dismutase [Mn] Mitochondrial, SOD2 |
| Accession: | P04179 |
| Sequence: | Lys25-Lys222 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Superoxide Dismutase [Mn] Mitochondrial is produced by our E.coli expression system and the target gene encoding Lys25-Lys222 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 23.7 kDa |
| AP Mol Mass: | 23 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM Tris;100mM NaCl;50% glycerol;pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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system_update_altDatasheetHuman SOD2/Mn-SOD Recombinant Protein Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that
