Human SNRPD2 Recombinant Protein (RPPB4756)
- SKU:
- RPPB4756
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P62316
Description
| Product Name: | Human SNRPD2 Recombinant Protein |
| Product Code: | RPPB4756 |
| Size: | 20µg |
| Species: | Human |
| Target: | SNRPD2 |
| Synonyms: | Small nuclear ribonucleoprotein Sm D2, Sm-D2, snRNP core protein D2, SNRPD2, SNRPD1, SMD2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The SNRPD2 solution contains�20mM Tris-HCl buffer (pH8.0), 50% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSLLNKPKSE MTPEELQKRE EEEFNTGPLS VLTQSVKNNT QVLINCRNNK KLLGRVKAFD RHCNMVLENV KEMWTEVPKS GKGKKKSKPV NKDRYISKMF LRGDSVIVVL RNPLIAGK |
SNRPD2 is a member of the small nuclear ribonucleoprotein core protein family. SNRPD2 is a small nuclear ribonucleoprotein (snRNPs) which comprises the spliceosome in eukaryotes. SNRPD2 is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis.
SNRPD2 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 138 amino acids (1-118 a.a.) and having a molecular mass of 15.6kDa. The SNRPD2 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | snRNP D2: Required for pre-mRNA splicing. Required for snRNP biogenesis. Belongs to the snRNP core protein family. |
| UniProt Protein Details: | Protein type:RNA splicing; Spliceosome Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: small nuclear ribonucleoprotein complex; nucleoplasm; spliceosome; snRNP U1; cytosol; U12-dependent spliceosome Molecular Function:protein binding Biological Process: nuclear mRNA splicing, via spliceosome; spliceosomal snRNP biogenesis; RNA splicing; spliceosome assembly; gene expression |
| NCBI Summary: | The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
| UniProt Code: | P62316 |
| NCBI GenInfo Identifier: | 51338666 |
| NCBI Gene ID: | 6633 |
| NCBI Accession: | P62316.1 |
| UniProt Related Accession: | P62316 |
| Molecular Weight: | |
| NCBI Full Name: | Small nuclear ribonucleoprotein Sm D2 |
| NCBI Synonym Full Names: | small nuclear ribonucleoprotein D2 polypeptide |
| NCBI Official Symbol: | SNRPD2�� |
| NCBI Official Synonym Symbols: | SMD2; Sm-D2; SNRPD1�� |
| NCBI Protein Information: | small nuclear ribonucleoprotein Sm D2 |
| UniProt Protein Name: | Small nuclear ribonucleoprotein Sm D2 |
| UniProt Synonym Protein Names: | snRNP core protein D2 |
| Protein Family: | Probable small nuclear ribonucleoprotein |
| UniProt Gene Name: | SNRPD2�� |
| UniProt Entry Name: | SMD2_HUMAN |
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