Human SNRPD1 Recombinant Protein (RPPB4755)
- SKU:
- RPPB4755
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P62314
Description
| Product Name: | Human SNRPD1 Recombinant Protein |
| Product Code: | RPPB4755 |
| Size: | 10µg |
| Species: | Human |
| Target: | SNRPD1 |
| Synonyms: | Small nuclear ribonucleoprotein Sm D1, Sm-D1, Sm-D autoantigen, snRNP core protein D1, SNRPD1, SMD1, SNRPD, HsT2456. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | SNRPD1 is supplied in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 80% as determined by SDS-PAGE. |
SNRPD1 is a small nuclear ribonucleoprotein which is a member of the SNRNP core protein family. SNRPD1 may act as a charged protein scaffold to stimulate SNRNP assembly or strengthen SNRNP-SNRNP interactions via nonspecific electrostatic contacts with RNA. In the autoimmune disease systemic lupus erythematosus, antinuclear antibodies are developed with Sm specificity.
SNRPD1 Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 14,306 Dalton. SNRPD1 is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | snRNP D1: May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA. Belongs to the snRNP core protein family. |
| UniProt Protein Details: | Protein type:RNA splicing; Spliceosome; RNA-binding Chromosomal Location of Human Ortholog: 18q11.2 Cellular Component: nucleoplasm; small nuclear ribonucleoprotein complex; snRNP U1; cytosol; nucleus; U12-dependent spliceosome Molecular Function:protein binding; RNA binding Biological Process: nuclear mRNA splicing, via spliceosome; spliceosomal snRNP biogenesis; RNA splicing; spliceosome assembly; gene expression |
| NCBI Summary: | This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] |
| UniProt Code: | P62314 |
| NCBI GenInfo Identifier: | 51338665 |
| NCBI Gene ID: | 6632 |
| NCBI Accession: | P62314.1 |
| UniProt Secondary Accession: | P62314,P13641, B5BTZ1, |
| UniProt Related Accession: | P62314 |
| Molecular Weight: | 119 |
| NCBI Full Name: | Small nuclear ribonucleoprotein Sm D1 |
| NCBI Synonym Full Names: | small nuclear ribonucleoprotein D1 polypeptide 16kDa |
| NCBI Official Symbol: | SNRPD1�� |
| NCBI Official Synonym Symbols: | SMD1; SNRPD; Sm-D1; HsT2456�� |
| NCBI Protein Information: | small nuclear ribonucleoprotein Sm D1; Sm-D autoantigen; snRNP core protein D1; small nuclear ribonucleoprotein D1 polypeptide 16kDa pseudogene |
| UniProt Protein Name: | Small nuclear ribonucleoprotein Sm D1 |
| UniProt Synonym Protein Names: | Sm-D autoantigen; snRNP core protein D1 |
| Protein Family: | Small nuclear ribonucleoprotein |
| UniProt Gene Name: | SNRPD1�� |
| UniProt Entry Name: | SMD1_HUMAN |
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