Human SNRNP25 Recombinant Protein (RPPB4746)

(No reviews yet) Write a Review
SKU:
RPPB4746

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human SNRNP25 Recombinant Protein
Product Code:RPPB4746
Size:20µg
Species:Human
Target:SNRNP25
Synonyms:U11/U12 small nuclear ribonucleoprotein 25 kDa protein, U11/U12 snRNP 25 kDa protein, U11/U12-25K, Minus-99 protein, SNRNP25, C16orf33.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:SNRNP25 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 20% glycerol, 2mM DTT and 0.2M NaCl.
Stability:SNRNP25 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MDVFQEGLAM VVQDPLLCDL PIQVTLEEVN SQIALEYGQA MTVRVCKMDG EVMPVVVVQS ATVLDLKKAI QRYVQLKQER EGGIQHISWS YVWRTYHLTS AGEKLTEDRK KLRDYGIRNR DEVSFIKKLR QK

SNRNP25 is a member of the small nuclear ribonucleoprotein core protein family. SNRNP25 is a component of the U12-type spliceosome which is found in some eukaryotes and removes U12-type introns that are rare and have distinct splice consensus signals. The U12-type spliceosome is comprised of several small nuclear RNAs and associated proteins.

SNRNP25 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 152 amino acids (1-132 a.a.) and having a molecular mass of 17.4kDa.SNRNP25 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:SNRNP25: Component of the U11/U12 snRNPs that are part of the U12- type spliceosome.
UniProt Protein Details:

Protein type:RNA splicing; RNA processing

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: nucleoplasm; intercellular bridge; cytoplasm; nucleus; U12-dependent spliceosome

Biological Process: RNA splicing; mRNA processing

NCBI Summary:Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 25K protein that is a component of the U12-type spliceosome. [provided by RefSeq, Apr 2010]
UniProt Code:Q9BV90
NCBI GenInfo Identifier:12655062
NCBI Gene ID:79622
NCBI Accession:BC001381
UniProt Secondary Accession:Q9BV90,Q1W6H3, Q6IEF8, Q9H5W4,
UniProt Related Accession:Q9BV90
Molecular Weight:15,270 Da
NCBI Full Name:Homo sapiens small nuclear ribonucleoprotein 25kDa (U11/U12), mRNA
NCBI Synonym Full Names:small nuclear ribonucleoprotein U11/U12 subunit 25
NCBI Official Symbol:SNRNP25��
NCBI Official Synonym Symbols:C16orf33��
NCBI Protein Information:U11/U12 small nuclear ribonucleoprotein 25 kDa protein
UniProt Protein Name:U11/U12 small nuclear ribonucleoprotein 25 kDa protein
UniProt Synonym Protein Names:Minus-99 protein
Protein Family:U11/U12 small nuclear ribonucleoprotein 25 kDa protein
UniProt Gene Name:SNRNP25��
UniProt Entry Name:SNR25_HUMAN
View AllClose

Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9BV90
View AllClose

Related Products