Human SNRNP25 Recombinant Protein (RPPB4746)
- SKU:
- RPPB4746
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9BV90
Description
| Product Name: | Human SNRNP25 Recombinant Protein |
| Product Code: | RPPB4746 |
| Size: | 20µg |
| Species: | Human |
| Target: | SNRNP25 |
| Synonyms: | U11/U12 small nuclear ribonucleoprotein 25 kDa protein, U11/U12 snRNP 25 kDa protein, U11/U12-25K, Minus-99 protein, SNRNP25, C16orf33. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | SNRNP25 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 20% glycerol, 2mM DTT and 0.2M NaCl. |
| Stability: | SNRNP25 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MDVFQEGLAM VVQDPLLCDL PIQVTLEEVN SQIALEYGQA MTVRVCKMDG EVMPVVVVQS ATVLDLKKAI QRYVQLKQER EGGIQHISWS YVWRTYHLTS AGEKLTEDRK KLRDYGIRNR DEVSFIKKLR QK |
SNRNP25 is a member of the small nuclear ribonucleoprotein core protein family. SNRNP25 is a component of the U12-type spliceosome which is found in some eukaryotes and removes U12-type introns that are rare and have distinct splice consensus signals. The U12-type spliceosome is comprised of several small nuclear RNAs and associated proteins.
SNRNP25 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 152 amino acids (1-132 a.a.) and having a molecular mass of 17.4kDa.SNRNP25 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SNRNP25: Component of the U11/U12 snRNPs that are part of the U12- type spliceosome. |
| UniProt Protein Details: | Protein type:RNA splicing; RNA processing Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: nucleoplasm; intercellular bridge; cytoplasm; nucleus; U12-dependent spliceosome Biological Process: RNA splicing; mRNA processing |
| NCBI Summary: | Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 25K protein that is a component of the U12-type spliceosome. [provided by RefSeq, Apr 2010] |
| UniProt Code: | Q9BV90 |
| NCBI GenInfo Identifier: | 12655062 |
| NCBI Gene ID: | 79622 |
| NCBI Accession: | BC001381 |
| UniProt Secondary Accession: | Q9BV90,Q1W6H3, Q6IEF8, Q9H5W4, |
| UniProt Related Accession: | Q9BV90 |
| Molecular Weight: | 15,270 Da |
| NCBI Full Name: | Homo sapiens small nuclear ribonucleoprotein 25kDa (U11/U12), mRNA |
| NCBI Synonym Full Names: | small nuclear ribonucleoprotein U11/U12 subunit 25 |
| NCBI Official Symbol: | SNRNP25�� |
| NCBI Official Synonym Symbols: | C16orf33�� |
| NCBI Protein Information: | U11/U12 small nuclear ribonucleoprotein 25 kDa protein |
| UniProt Protein Name: | U11/U12 small nuclear ribonucleoprotein 25 kDa protein |
| UniProt Synonym Protein Names: | Minus-99 protein |
| Protein Family: | U11/U12 small nuclear ribonucleoprotein 25 kDa protein |
| UniProt Gene Name: | SNRNP25�� |
| UniProt Entry Name: | SNR25_HUMAN |
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