Human SIRPG Recombinant Protein (RPPB4690)

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SKU:
RPPB4690
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9P1W8

Description

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Product Name:Human SIRPG Recombinant Protein
Product Code:RPPB4690
Size:20µg
Species:Human
Target:SIRPG
Synonyms:Signal Regulatory Protein Gamma, CD172 Antigen-Like Family Member B, Signal-Regulatory Protein Beta-2, Signal-Regulatory Protein Gamma, CD172g Antigen, SIRP-Gamma, SIRP-B2, SIRPB2, Signal-Regulatory Protein Beta 2, SIRP-Beta-2, SIRP Beta 2, SIRPgamma, BA77C3.1, CD172g.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered colorless solution.
Formulation:SIRPG protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 20% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:ADPEEELQMI QPEKLLLVTV GKTATLHCTV TSLLPVGPVL WFRGVGPGRE LIYNQKEGHF PRVTTVSDLT KRNNMDFSIR ISSITPADVG TYYCVKFRKG SPENVEFKSG PGTEMALGAK PSAPVVLGPA ARTTPEHTVS FTCESHGFSP RDITLKWFKN GNELSDFQTN VDPTGQSVAY SIRSTARVVL DPWDVRSQVI CEVAHVTLQG DPLRGTANLS EAIRVPPTLE VTQQPMRVGN QVNVTCQVRK FYPQSLQLTW SENGNVCQRE TASTLTENKD GTYNWTSWFL VNISDQRDDV VLTCQVKHDG QLAVSKRLAL EVTVHQKDQS SDATPLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH

Signal-Regulatory Protein Gamma (SIRPG) belongs to the signal-regulatory protein (SIRP) family whose members are receptor-type transmembrane glycoproteins which negatively regulate the receptor tyrosine kinase-coupled signaling processes. SIRPG is also a part of the immunoglobulin superfamily.

SIRPG Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 574 amino acids (29-360a.a.) and having a molecular mass of 64.0kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).SIRPG is expressed with a 239 amino acids hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
NCBI Summary:The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Code:Q9P1W8
NCBI GenInfo Identifier:124053651
NCBI Gene ID:55423
NCBI Accession:Q9P1W8.3
UniProt Secondary Accession:Q9P1W8,Q5D051, Q5JV25, Q5MKL4, Q8WWA5, Q9NQK8, B1AKP6
UniProt Related Accession:Q9P1W8
Molecular Weight:29,967 Da
NCBI Full Name:Signal-regulatory protein gamma
NCBI Synonym Full Names:signal regulatory protein gamma
NCBI Official Symbol:SIRPG��
NCBI Official Synonym Symbols:CD172g; SIRPB2; SIRP-B2; bA77C3.1; SIRPgamma��
NCBI Protein Information:signal-regulatory protein gamma
UniProt Protein Name:Signal-regulatory protein gamma
UniProt Synonym Protein Names:CD172 antigen-like family member B; Signal-regulatory protein beta-2; SIRP-b2; SIRP-beta-2; CD_antigen: CD172g
Protein Family:Signal-regulatory protein
UniProt Gene Name:SIRPG��
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