Human SIKE1 Recombinant Protein (RPPB4684)
- SKU:
- RPPB4684
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9BRV8
Description
| Product Name: | Human SIKE1 Recombinant Protein |
| Product Code: | RPPB4684 |
| Size: | 10µg |
| Species: | Human |
| Target: | SIKE1 |
| Synonyms: | Suppressor Of IKBKE 1, SIKE, Suppressor Of IKK Epsilon, SuppressorOf IKK-Epsilon. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | SIKE1 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 30%glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greaterthan 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSCTIEK ILTDAKTLLE RLREHDAAAE SLVDQSAALH RRVAAMREAGTALPDQYQED ASDMKDMSKY KPHILLSQEN TQIRDLQQEN RELWISLEEH QDALELIMSK YRKQMLQLMVAKKAVDAEPV LKAHQSHSAE IESQIDRICE MGEVMRKAVQ VDDDQFCKIQ EKLAQLELEN KELRELLSIS SESLQARKEN SMDTASQAIK |
| UniProt Code: | Q9BRV8 |
Suppressor of IKBKE 1 also known as SIKE1 belongs to the SIKE family. SIKE interacts with IKK-epsilon and TBK1 and function as a suppressor of TLR3. In addition, SIKE1 perform by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 andDDX58/RIG-I. SIKE1 does not inhibit NF-kappa-B activation pathways.
SIKE1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 230 amino acids (1-207 a.a) andhaving a molecular mass of 26.1kDa.SIKE1 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
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