Cell Biology Recombinant Proteins
Human SIGLEC5 Recombinant Protein (RPES5215)
- SKU:
- RPES5215
Description
Human SIGLEC5 Recombinant Protein
SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It's in the SIGLEC (sialic acid binding Ig-like lectin) family and is part of the immunoglobulin superfamily. Monocytic/myeloid-lineage cells express SIGLEC5. It's prevalent in blood leukocytes, the spleen, bone marrow, and at lesser amounts in lymph node; lung; appendix; placenta; pancreas; and thymus. It's also expressed by neutrophils and macrophages, although it isn't found in myelomonocytic cell lines. The SIGLEC5 adhesion molecule is a putative adhesion molecule that functions in sialic-acid dependent cell binding. It binds equally to alpha-2;3- and alpha-2;6- linked sialic acid. The sialic acid recognition site may be hidden by cis interactions between the sialic acids on the same cell surface. Human SIGLEC5 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human SIGLEC5 Recombinant Protein (RPES5215) |
| Product Code: | RPES5215 |
| Size: | 50µg |
| Species: | Human |
| Expressed Host: | HEK293 Cells |
| Synonyms: | Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, CD170,CD33L2,OB-BP2,OBBP,OBBP2,SIGLEC-5,SIGLEC5 |
| Accession: | O15389 |
| Sequence: | Met 1-Thr 434 |
| Fusion tag: | |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human SIGLEC5 (O15389) (Met1-Thr 434) was expressed with six amino acids (LEVLFQ) at the C-terminus was expressed and purified. |
| Purity: | > 85 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 47.2 kDa |
| AP Mol Mass: | 67 kDa |
| Formulation: | Lyophilized from sterile PBS; pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Cell Biology |
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