Human SH3BGRL Recombinant Protein (RPPB4672)

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SKU:
RPPB4672
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
O75368

Description

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Product Name:Human SH3BGRL Recombinant Protein
Product Code:RPPB4672
Size:20µg
Species:Human
Target:SH3BGRL
Synonyms:SH3 domain-binding glutamic acid-rich-like protein, SH3BGRL, SH3BGR.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:SH3BGRL protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.15M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMVIRVY IASSSGSTAI KKKQQDVLGF LEANKIGFEE KDIAANEENR KWMRENVPEN SRPATGYPLP PQIFNESQYR GDYDAFFEAR ENNAVYAFLG LTAPPGSKEA EVQAKQQA

SH3 domain-binding glutamic acid-rich-like protein (SH3BGRL) belongs to the human SH3BGR family. SH3BGRL gene which is located to chromosome Xq13.3, encodes a small protein of 114 amino acids that is extensively expressed in various tissues including liver and blood. SH3BGRL protein contains a prolinerich sequence (PLPPQIF), which is comprsed of both the SH3 binding (PXXP)3 and the Homer EVH1 binding (PPXXF)4 motif.

SH3BGRL Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 138 amino acids (1-114 a.a) and having a molecular mass of 15.3kDa.SH3BGRL is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:SH3BGRL: Belongs to the SH3BGR family.
UniProt Protein Details:

Protein type:Adaptor/scaffold

Chromosomal Location of Human Ortholog: Xq21.1

Cellular Component: cytoplasm; extracellular space; nucleus

Molecular Function:SH3/SH2 adaptor activity

UniProt Code:O75368
NCBI GenInfo Identifier:12230575
NCBI Gene ID:6451
NCBI Accession:O75368.1
UniProt Secondary Accession:O75368,Q3SYL1, Q5JT50, Q6FIE8, Q9H0N8,
UniProt Related Accession:O75368
Molecular Weight:13kDa
NCBI Full Name:SH3 domain-binding glutamic acid-rich-like protein
NCBI Synonym Full Names:SH3 domain binding glutamate rich protein like
NCBI Official Symbol:SH3BGRL��
NCBI Official Synonym Symbols:SH3BGR; HEL-S-115��
NCBI Protein Information:SH3 domain-binding glutamic acid-rich-like protein
UniProt Protein Name:SH3 domain-binding glutamic acid-rich-like protein
Protein Family:SH3 domain-binding glutamic acid-rich-like protein
UniProt Gene Name:SH3BGRL��
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