Description
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Human SGTA Recombinant Protein
Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein ? (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV-1. It also interacts with SARS-CoV Accessory Protein 7a, DNAJC5 and DNAJC5B. However, its function is not known. Since this transcript is expressed ubiquitously in various tissues, SGTA may serve a housekeeping function.
| Product Name: | Human SGTA Recombinant Protein (RPES4906) |
| Product Code: | RPES4906 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha, Alpha-SGT, Vpu-Binding Protein, UBP, SGTA, SGT, SGT1 |
| Accession: | O43765 |
| Sequence: | Met 1-Glu313 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein alpha is produced by our E.coli expression system and the target gene encoding Met1-Glu313 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 36.2 kDa |
| AP Mol Mass: | 35 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Immunology |