SERPINB3-related diseases include non-small cell lung cancer and cervical squamous cell carcinoma.The innate immune system is one of the many pathways through which SerpinB3 works. It inhibits the host immune response against tumor cells by acting like a papain-like cysteine protease inhibitor.It also inhibits UV-induced apoptosis by inhibiting the activity of c-Jun NH(2) -terminal kinase (JNK1). Human SerpinB3/SCCA1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human SerpinB3/SCCA1 Recombinant Protein (RPES4637)
Product Code:
RPES4637
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Serpin B3, Protein T4-A, Squamous cell carcinoma antigen 1, SCCA-1,serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3, serpin peptidase inhibitor, clade B (ovalbumin), member 3, Squamous cell carcinoma antigen 1,T4-A,SCCA1,HsT1196,SCC,SCCA-1,SCCA-PD
Accession:
P29508
Sequence:
Met 1-Pro390
Fusion tag:
N-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Serine Protease Inhibitor-clade B3 is produced by our E.coli expression system and the target gene encoding Met1-Pro390 is expressed with a 6His tag at the N-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
46.0 kDa
AP Mol Mass:
40-55 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
system_update_altDatasheetHuman SerpinB3/SCCA1 Recombinant Protein Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease in
system_update_altDatasheetHuman SerpinB3/SCCA1 Recombinant Protein SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were
system_update_altDatasheetMouse SerpinB3/SCCA1 Recombinant Protein Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental bi